Shivering Shavenbaby

The Scientist magazine, October 2010.

The paper

N. Frankel et al., “Phenotypic robustness conferred by apparently redundant transcriptional enhancers,” Nature, 466:490-93, 2010.

The finding

Are redundant copies of noncoding DNA sequences due to poor genomic housekeeping, or do they function to improve the organism’s chances of survival? David Stern at Princeton University and colleagues attacked this question by looking at duplicate or “shadow” versions of enhancers, noncoding regions that regulate and promote gene expression. Read More >